- SYSTEMS X - MEDICAL RESEARCH & DEVELOPMENT
VirX - A systems approach to Ub/HDAC6/Aggresome pathway and Ubiquitin proteasome system in viral disease. Consortium with 5 other Swiss laboratories i.e. Patrick Matthias (FMI Basel), Urs Greber (University of Zurich), Heinz Gut (FMI Basel), Jörg Stelling (ETH-BSSE), Laurent Kaiser, Mirco Schmolke (University of Geneva).
Bernd Wollscheid lab, D-HEST, Institute of Molecular Systems Biology, ETH Zurich, Switzerland.
Using ligand-based receptor (LRC) capture to identify cellular surface proteins and receptor candidates that are enriched in the vicinity of viruses upon binding to the cell surface.
THIS WORK WAS PUBLISHED IN NATURE COMMUNICATIONS (Sobotzki et al. 2018)
FREEZE-ETCH CRYO EM, CLEM
Jiro Usukura, Institute of Structural Biology, Nagoya University, Japan. (Yohei Yamauchi is a guest professor here)
Paul Verkade, School of Biochemistry, Wolfson Bioimaging facility, University of Bristol.
To gain ultrastructural insight and high-resolution images of virus uncoating, virus entry.
CHEMICAL PROTEIN SYNTHESIS