INTERDISCIPLINARY

- SYSTEMS X - MEDICAL RESEARCH & DEVELOPMENT

(2015-2018)

VirX - A systems approach to Ub/HDAC6/Aggresome pathway and Ubiquitin proteasome system in viral disease. Consortium with 5 other Swiss laboratories i.e. Patrick Matthias (FMI Basel), Urs Greber (University of Zurich), Heinz Gut (FMI Basel), Jörg Stelling (ETH-BSSE), Laurent Kaiser, Mirco Schmolke (University of Geneva).

SURFACE PROTEOMICS

Bernd Wollscheid lab, D-HEST, Institute of Molecular Systems Biology, ETH Zurich, Switzerland.

Using ligand-based receptor (LRC) capture to identify cellular surface proteins and receptor candidates that are enriched in the vicinity of viruses upon binding to the cell surface.

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THIS WORK WAS PUBLISHED IN NATURE COMMUNICATIONS (Sobotzki et al. 2018)

FREEZE-ETCH CRYO EM, CLEM

Jiro Usukura, Institute of Structural Biology, Nagoya University, Japan. (Yohei Yamauchi is a guest professor here)

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Paul Verkade, School of Biochemistry, Wolfson Bioimaging facility, University of Bristol.

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To gain ultrastructural insight and high-resolution images of virus uncoating, virus entry.

CHEMICAL PROTEIN SYNTHESIS

coming soon

MICROFLUIDICS

coming soon